Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730164 | 0.79 | HRH4 (0.33) | HRH4 | |
| SCHEMBL1705475 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL24454867 | 0.68 | RAB9A (0.53) | — | |
| SCHEMBL7488164 | 0.68 | GABRP (0.40) | — | |
| SCHEMBL24251890 | 0.68 | GABRP (0.39) | — | |
| SCHEMBL6490027 | 0.67 | TDP1 (0.57) | — | |
| SCHEMBL25391210 | 0.67 | MMP2 (0.55) | — | |
| SCHEMBL4984458 | 0.65 | MAPT (0.33) | — | |
| SCHEMBL25006829 | 0.64 | KDM4E (0.39) | — | |
| SCHEMBL17751215 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124485-B | Sulfoxide-containing benzoxazole derivative, and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-12-15 | — | — | CN | disclosed |
| CN-115124485-A | Benzoxazole derivatives containing sulfoxide as well as preparation method and application thereof | 中国医学科学院药物研究所 | 2022-09-30 | — | — | CN | disclosed |
| CN-105431427-A | Novel PDE4 inhibitor | MEIJI SEIKA PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |