SCHEMBL28056360

SCHEMBL28056360

O=NOC(=O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
MAPT P10636 2/20 0.60
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
HTT P42858 3/20 0.54
CTSD P07339 1/20 0.51
KMT2A Q03164 2/20 0.51
GAA P10253 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
NCOA1 Q15788 1/20 0.48
NCOA3 Q9Y6Q9 1/20 0.48
MEN1 O00255 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551442 0.82 ALDH1A1 (0.61) ALDH1A1MAPTNPC1RAB9AHTT
SCHEMBL2289848 0.82 ALDH1A1 (0.61) ALDH1A1MAPTNPC1RAB9AHTT
SCHEMBL14600783 0.81 NPC1 (0.62) ALDH1A1MAPTNPC1RAB9AHTT
SCHEMBL827585 0.80 ALDH1A1 (0.59) ALDH1A1MAPTNPC1RAB9AHTT
SCHEMBL1706209 0.79 CTSD (0.56) ALDH1A1MAPTNPC1RAB9AHTT
SCHEMBL23037576 0.79 ALDH1A1 (0.58) ALDH1A1MAPTNPC1RAB9AHTT
SCHEMBL1133328 0.79 ALDH1A1 (0.58) ALDH1A1MAPTNPC1RAB9AHTT
SCHEMBL195311 0.79 ALDH1A1 (0.62) ALDH1A1MAPTNPC1RAB9AHTT
SCHEMBL9647951 0.79 ALDH1A1 (0.58) ALDH1A1MAPTNPC1RAB9AHTT
SCHEMBL8576742 0.79 CTSD (0.59) ALDH1A1MAPTNPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106431983-B A kind of 2- benzyloxies benzonitrile class compound and preparation method thereof 信阳师范学院 2018-06-15 CN claimed
CN-103575730-B A kind of kit and using method thereof detecting protein alkylation dressing agent PEG Modifying Capability SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) 2016-03-30 CN claimed
CN-101575253-B Application of fullerene as catalyst in catalytic hydrogenation reaction of nitro aromatic compound NANJING UNIVERSITY OF TECHNOLOGY 2012-12-19 CN claimed
CN-101648840-B Application of fullerene used as catalyst for catalytic hydrogenation reaction of nitro group in nitroaromatic compounds under light irradiation NANJING UNIVERSITY (CN) 2012-02-01 CN claimed
CN-101224422-B SiO2 supported nanometer silver catalyst, preparing method and applications thereof NANJING UNIVERSITY OF TECHNOLOGY 2010-06-16 CN claimed
CN-101648840-A Application of fullerene used as catalyst for catalytic hydrogenation reaction of nitro group in nitroaromatic compounds under light irradiation NANJING UNIVERSITY OF TECHNOLOGY 2010-02-17 CN claimed
CN-101575253-A Application of fullerene as catalyst in catalytic hydrogenation reaction of nitro aromatic compound NANJING UNIVERSITY OF TECHNOLOGY (CN) 2009-11-11 CN claimed
CN-101224422-A SiO2 supported nanometer silver catalyst, preparing method and applications thereof NANJING UNIVERSITY OF TECHNOLOGY (CN) 2008-07-23 CN claimed
CN-106146232-B The method that aromatic nitro compound selective hydrogenation prepares aromatic amine compound 长春工业大学 2019-09-20 CN disclosed
CN-105753738-B A kind of method of nitrobenzoyl catalytic hydrogenation of nitriles synthesizing amino benzonitrile 长春工业大学 2018-10-12 CN disclosed
CN-105753738-A Method for synthesizing cyanoaniline through nitrobenzonitrile catalytic hydrogenation 长春工业大学 2016-07-13 CN disclosed
CN-101575253-B Application of fullerene as catalyst in catalytic hydrogenation reaction of nitro aromatic compound NANJING UNIVERSITY OF TECHNOLOGY 2012-12-19 CN disclosed
CN-101648840-B Application of fullerene used as catalyst for catalytic hydrogenation reaction of nitro group in nitroaromatic compounds under light irradiation NANJING UNIVERSITY (CN) 2012-02-01 CN disclosed
CN-101224422-B SiO2 supported nanometer silver catalyst, preparing method and applications thereof NANJING UNIVERSITY OF TECHNOLOGY 2010-06-16 CN disclosed
CN-101648840-A Application of fullerene used as catalyst for catalytic hydrogenation reaction of nitro group in nitroaromatic compounds under light irradiation NANJING UNIVERSITY OF TECHNOLOGY 2010-02-17 CN disclosed
CN-101575253-A Application of fullerene as catalyst in catalytic hydrogenation reaction of nitro aromatic compound NANJING UNIVERSITY OF TECHNOLOGY (CN) 2009-11-11 CN disclosed
CN-101224422-A SiO2 supported nanometer silver catalyst, preparing method and applications thereof NANJING UNIVERSITY OF TECHNOLOGY (CN) 2008-07-23 CN disclosed