Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | CASR | P41180 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22738606 | 0.71 | ALDH1A1 (0.46) | ADRA2CSLC6A4CASRKMT2AADRA1B | |
| SCHEMBL30826559 | 0.70 | ALDH1A1 (0.52) | ADRA2CSLC6A4ADRA1BCYP2C9ALDH1A1 | |
| SCHEMBL21217295 | 0.70 | ALDH1A1 (0.52) | ADRA2CSLC6A4ADRA1BCYP2C9ALDH1A1 | |
| SCHEMBL28653710 | 0.69 | ADRA2A (0.47) | ADRA2CSLC6A4KMT2AADRA1BCYP2C9 | |
| Naphthalene SCHEMBL28055820 | 0.69 | CYP2A6 (0.44) | KMT2AHTTALDH1A1CYP1A2 | |
| SCHEMBL3799100 | 0.69 | ALDH1A1 (0.50) | ADRA2CSLC6A4ADRA1BCYP2C9ALDH1A1 | |
| SCHEMBL5609974 | 0.69 | ALDH1A1 (0.50) | ADRA2CSLC6A4CASRSLC6A2HTR2C | |
| SCHEMBL10409137 | 0.68 | CYP2C9 (0.46) | ADRA2CSLC6A4CASRSLC6A2HTR2C | |
| SCHEMBL22326119 | 0.68 | ALDH1A1 (0.54) | ADRA2CSLC6A4ADRA1BCYP2C9ALDH1A1 | |
| SCHEMBL3247528 | 0.68 | ALDH1A1 (0.54) | ADRA2CSLC6A4CASRSLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418927-A | Low dielectric constant material film and preparation method thereof | SHANGHAI ADVANCED RES INST CAS | 2016-03-23 | — | — | CN | disclosed |