Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825160 | 0.82 | TSHR (0.45) | L3MBTL1RAB9ATSHRLMNAPOLB | |
| SCHEMBL2950398 | 0.82 | GLA (0.49) | L3MBTL1RAB9ATSHRLMNAPOLB | |
| SCHEMBL27339301 | 0.78 | ALDH1A1 (0.49) | L3MBTL1RAB9ATSHRALDH1A1TNF | |
| SCHEMBL11701401 | 0.77 | TSHR (0.39) | RAB9ATSHRLMNAPOLBALDH1A1 | |
| SCHEMBL17662300 | 0.77 | GLA (0.45) | TSHRPOLB | |
| SCHEMBL1127670 | 0.76 | L3MBTL1 (0.63) | L3MBTL1RAB9ATSHRLMNAPOLB | |
| SCHEMBL3970458 | 0.76 | ALDH1A1 (0.41) | RAB9ATSHRLMNAALDH1A1CYP1A2 | |
| SCHEMBL1403598 | 0.75 | NAAA (0.47) | L3MBTL1RAB9ATSHRLMNAPOLB | |
| SCHEMBL2954981 | 0.75 | GLA (0.42) | TSHRLMNAPOLBALDH1A1CYP1A2 | |
| SCHEMBL1446480 | 0.74 | PRKAB2 (0.39) | L3MBTL1TSHRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732637-B | Heteroaromatic compounds and their use in medicine | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-105732637-A | Hetero-aromatic compounds and applications thereof in pharmacy | 广东东阳光药业有限公司 | 2016-07-06 | — | — | CN | disclosed |