Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 5/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.31 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14976051 | 0.86 | FLT1 (0.34) | ADRA1DGPR35KDM4EALDH1A1GLA | |
| SCHEMBL14976966 | 0.85 | KDM4E (0.34) | ADRA1DGPR35KDM4EALDH1A1 | |
| SCHEMBL14976460 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL14976103 | 0.81 | ADRA1D (0.34) | ADRA1DGPR35KDM4EALDH1A1GLA | |
| SCHEMBL16583136 | 0.76 | P2RX1 (0.35) | GPR35KDM4EALDH1A1HPGDMRGPRX4 | |
| SCHEMBL28057064 | 0.75 | LMNA (0.40) | GPR35ALDH1A1FLT1FLT4KDR | |
| SCHEMBL27816654 | 0.75 | AKR1C2 (0.41) | GPR35KDM4EALDH1A1GAAFLT1 | |
| SCHEMBL28056987 | 0.73 | FLT1 (0.40) | GPR35FLT1FLT4KDRPDK1 | |
| SCHEMBL14698422 | 0.71 | KDM4E (0.37) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL16583090 | 0.70 | KDM4E (0.33) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556141-B2 | Process for preparing N-substituted 1H-pyrazole-5-carboxylate compounds and derivatives thereof | BASF SE (DE) | 2017-01-31 | — | — | US | disclosed |
| EP-2782910-B1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF | BASF SE (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-20150087843-A1 | Process for preparing N-substituted 1H-pyrazole-5-carboxylate compounds and derivatives thereof | BASF SE (DE) | 2015-03-26 | — | — | US | disclosed |
| EP-2782910-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF | BASF SE (DE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013076092-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF | BASF SE (DE) | 2013-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087843-A1 | Process for preparing N-substituted 1H-pyrazole-5-carboxylate compounds and derivatives thereof | CA5B, CA5A, PC | ADRA1D 3348/4885GPR35 1707/4885KDM4E 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.