SCHEMBL1817029

SCHEMBL1817029

N=C(NCc1ccccc1)N[N+](=O)[O-]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
CYP2C19 P33261 4/20 0.45
CYP2D6 P10635 2/20 0.45
LMNA P02545 1/20 0.45
ALOX12 P18054 2/20 0.44
HPGD P15428 2/20 0.44
CYP2C9 P11712 2/20 0.43
GAA P10253 2/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
POLB P06746 2/20 0.43
MAPT P10636 1/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 1/20 0.43
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
TSHR P16473 1/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10384368 0.83 MEN1 (0.48) ALDH1A1LMNAHPGDGAAMEN1
SCHEMBL10649915 0.83 ALOX15 (0.46) ALDH1A1LMNAKMT2AMAPTCYP1A2
SCHEMBL10858706 0.82 ALOX5 (0.55) CYP2C19CYP2D6LMNAHPGDMAPT
SCHEMBL10860569 0.82 KMT2A (0.48) CYP2C19HPGDKMT2AMAPTCYP1A2
SCHEMBL10859104 0.82 CYP19A1 (0.39) ALDH1A1CYP2C19CYP2D6LMNAALOX12
SCHEMBL10383500 0.82 ATG4B (0.47) ALDH1A1LMNAHPGDPOLBCASP3
SCHEMBL10383507 0.82 MMP13 (0.47) ALDH1A1CYP2C19CYP2D6HPGDCYP2C9
SCHEMBL7769614 0.82 HTT (0.54) ALDH1A1LMNAPOLBMAPT
SCHEMBL6677679 0.81 CYP19A1 (0.44) ALDH1A1ALOX12HPGDGAAMEN1
SCHEMBL1273847 0.79 ALDH1A1 (0.60) ALDH1A1CYP2C19CYP2D6LMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102656230-B Guanidine derivative is as the purposes of epoxy resin curing accelerator Aozer Chemical Co.,Ltd. (DE) 2016-04-06 CN claimed
US-9238706-B2 Use of guanidine derivatives as curing accelerators for epoxy resins ALZCHEM AG (DE) 2016-01-19 US claimed
EP-2496642-B1 USE OF GUANIDINE DERIVATIVES AS CURING ACCELERATORS FOR EPOXY RESINS ALZCHEM AG (DE) 2014-10-29 EP claimed
EP-2496642-A2 USE OF GUANIDINE DERIVATIVES AS CURING ACCELERATORS FOR EPOXY RESINS AlzChem AG (DE) 2012-09-12 EP claimed
CN-102656230-A Use of guanidine derivatives as curing accelerators for epoxy resins ALZCHEM TROSTBERG GMBH 2012-09-05 CN claimed
US-20120208925-A1 USE OF GUANIDINE DERIVATIVES AS CURING ACCELERATORS FOR EPOXY RESINS ALZCHEM TROSTBERG GMBH (DE) 2012-08-16 US claimed
WO-2011054945-A2 USE OF GUANIDINE DERIVATIVES AS CURING ACCELERATORS FOR EPOXY RESINS ALZCHEM TROSTBERG GMBH (DE) 2011-05-12 WO claimed
US-6680408-B2 REACTING S-METHYL NITROISOTHIOUREA WITH ALPHA-ETHYLBENZYLAMINE IN THE PRESENCE OF WATER AND ETHANOL MIXTURES TO FORM 1-(ALPHA-ETHYLBENZYL)-3-NITROGUANIDINE, USED AS PREEMERGENCE HERBICIDES BAYER CROPSCIENCE LP 2004-01-20 US claimed
US-20030236168-A1 PROCESSES FOR THE PREPARATION OF ALPHA-SUBSTITUTED BENZYLNITROGUANIDINES BAYER CORPORATION 2003-12-25 US claimed
US-4944788-A Substituted nitro and cyanoguanidines and their use for increasing crop yields AMERICAN CYANAMID COMPANY (US) 1990-07-31 US claimed
EP-0113070-B1 THE USE OF SUBSTITUTED NITRO AND CYANOGUANIDINES FOR INCREASING CROP YIELD AMERICAN CYANAMID COMPANY (US) 1988-01-13 EP claimed
EP-0113070-A1 The use of substituted nitro and cyanoguanidines for increasing crop yield AMERICAN CYANAMID COMPANY (US) 1984-07-11 EP claimed
US-20250257194-A1 A METHOD FOR THE PREPARATION OF AN EPOXY RESIN COMPOSITION FOR THE PRE-IMPREGNATION OF MATERIALS ALZCHEM TROSTBERG GMBH (DE) 2025-08-14 US disclosed
EP-4562073-A1 PROCESS FOR PRODUCING AN EPOXY RESIN COMPOSITION FOR PREIMPREGNATING MATERIALS AlzChem Trostberg GmbH (DE) 2025-06-04 EP disclosed
CN-119585337-A Method for preparing epoxy resin composition for material pre-impregnation 澳泽化学特罗斯特贝格有限公司 2025-03-07 CN disclosed
WO-2024022901-A1 PROCESS FOR PRODUCING AN EPOXY RESIN COMPOSITION FOR PREIMPREGNATING MATERIALS ALZCHEM TROSTBERG GMBH (DE) 2024-02-01 WO disclosed
US-4639268-A Nitro- and cyanoguanidines as selective preemergence herbicides and plant defoliants AMERICAN CYANAMID COMPANY (US) 1987-01-27 US disclosed
EP-0189579-A1 Substituted nitro and cyanoguanidines and their use for increasing crop yield AMERICAN CYANAMID COMPANY (US) 1986-08-06 EP disclosed
US-4594092-A Cytokinin-like response AMERICAN CYANAMID COMPANY (US) 1986-06-10 US disclosed
EP-0113070-A1 The use of substituted nitro and cyanoguanidines for increasing crop yield AMERICAN CYANAMID COMPANY (US) 1984-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236168-A1 PROCESSES FOR THE PREPARATION OF ALPHA-SUBSTITUTED BENZYLNITROGUANIDINES SRM, BPGM, GMPS ALDH1A1 952/4885CYP2C19 546/4885CYP2D6 548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.