Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14782975 | 0.85 | HTT (0.53) | RIPK1KMT2AHPGDPOLBMAPT | |
| SCHEMBL1671880 | 0.84 | KDM4E (0.48) | RIPK1KMT2AHPGDPOLBMAPT | |
| SCHEMBL18219781 | 0.78 | TSHR (0.52) | RIPK1POLBMAPTHDAC6SMN1; SMN2 | |
| SCHEMBL15471188 | 0.78 | ALDH1A1 (0.60) | RIPK1KMT2AHPGDPOLBMAPT | |
| SCHEMBL28221309 | 0.77 | P2RX7 (0.42) | KMT2AHPGDMAPTHDAC6HTT | |
| SCHEMBL13726222 | 0.77 | RIPK1 (0.74) | RIPK1HPGDMAPTHTTSMN1; SMN2 | |
| SCHEMBL19318518 | 0.77 | HPGD (0.53) | RIPK1KMT2AHPGDPOLBMAPT | |
| SCHEMBL14269014 | 0.74 | LIPG (0.49) | RIPK1KMT2APOLBHDAC6RAB9A | |
| SCHEMBL1709278 | 0.74 | MEN1 (0.57) | KMT2AHPGDMAPTCA2 | |
| SCHEMBL14667212 | 0.74 | KMT2A (0.65) | KMT2AHPGDNPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105523996-A | Amide-type derivative and its preparation method and use in medicine | JIANGSU HENGRUI MEDICINE CO | 2016-04-27 | — | — | CN | disclosed |