Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28057576 | 0.77 | MMP13 (0.46) | GPR84PPARAPPARDMAPTPPARG | |
| SCHEMBL28057541 | 0.76 | GPR84 (0.47) | GPR84PPARAPPARDMAPTPPARG | |
| SCHEMBL28492938 | 0.71 | CYP1A2 (0.54) | MAPTKCNH2NPC1ALDH1A1LMNA | |
| SCHEMBL28262433 | 0.70 | GPR84 (0.49) | GPR84MAPTKCNH2NPC1TDP1 | |
| SCHEMBL76135 | 0.66 | LMNA (0.64) | PPARAMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1283804 | 0.65 | MAOB (0.72) | PPARAPPARDMAPTPPARGALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL22437493 | 0.65 | LMNA (0.61) | PPARAMAPTALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27466889 | 0.65 | LMNA (0.61) | PPARAMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL18184942 | 0.65 | LMNA (0.61) | PPARAMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27364336 | 0.65 | LMNA (0.61) | PPARAMAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431416-A | 4-alkynyl imidazole derivative and medicine comprising same as active ingredient | KAKEN PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |