Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28057541 | 0.82 | GPR84 (0.47) | MCL1GPR84MAPTTDP1PPARA | |
| SCHEMBL28057539 | 0.77 | GPR84 (0.42) | MCL1GPR84MAPTTDP1PPARA | |
| SCHEMBL28262433 | 0.73 | GPR84 (0.49) | GPR84MAPTTDP1TAAR1MEN1 | |
| SCHEMBL1422384 | 0.70 | MMP2 (0.48) | MMP13MMP2MMP1MMP9 | |
| SCHEMBL4374627 | 0.69 | NR4A2 (0.71) | PPARAPPARGNR4A2TAAR1MRGPRX4 | |
| SCHEMBL27374286 | 0.68 | BRS3 (0.47) | MMP13MMP2MMP9GPR84MAPT | |
| SCHEMBL14953213 | 0.68 | PIN1 (0.72) | — | |
| SCHEMBL11019407 | 0.67 | PPARG (0.56) | MAPTTDP1PPARAPPARGMEN1 | |
| SCHEMBL11020355 | 0.67 | PPARG (0.56) | MAPTTDP1PPARAPPARGMEN1 | |
| SCHEMBL28261194 | 0.67 | TAAR1 (0.46) | GPR84MAPTTDP1TAAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431416-A | 4-alkynyl imidazole derivative and medicine comprising same as active ingredient | KAKEN PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |