Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 7/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28057546 | 0.74 | KDM5A (0.46) | SRD5A2PDE2AKDM5AKDM4CKDM5B | |
| SCHEMBL28057545 | 0.73 | SRD5A2 (0.43) | SRD5A2MAOBKDM5AKDM4CKDM5B | |
| SCHEMBL5758675 | 0.71 | SCN2A (0.54) | TYMP | |
| SCHEMBL8196736 | 0.69 | KIF11 (0.43) | MAOBKDM5AKDM4CKDM5BTYMP | |
| SCHEMBL9367898 | 0.67 | HRH1 (0.42) | MEN1KMT2A | |
| SCHEMBL5756074 | 0.67 | SCN2A (0.49) | PDE2A | |
| SCHEMBL29906422 | 0.67 | ALDH1A1 (0.48) | SRD5A2MAOBKDM4CMEN1KMT2A | |
| SCHEMBL26982493 | 0.67 | ALDH1A1 (0.48) | SRD5A2MAOBKDM4CMEN1KMT2A | |
| SCHEMBL5758137 | 0.66 | SCN2A (0.62) | — | |
| Hydrochloric Acid SCHEMBL8196875 | 0.66 | MAOB (0.44) | MAOBKDM5AKDM4CKDM5BTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431416-A | 4-alkynyl imidazole derivative and medicine comprising same as active ingredient | KAKEN PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |