Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339878 | 0.84 | HRH4 (0.38) | HRH1HRH4FDPSBAZ2BALDH1A1 | |
| SCHEMBL8957153 | 0.72 | MMP2 (0.44) | LMNAALDH1A1KDM4E | |
| SCHEMBL7520950 | 0.72 | — | — | |
| SCHEMBL5665905 | 0.71 | FDPS (0.47) | HRH1HRH4FDPSBAZ2B | |
| SCHEMBL4276190 | 0.69 | LMNA (0.44) | LMNAGLAALDH1A1HPGDKDM4E | |
| SCHEMBL889025 | 0.68 | — | — | |
| SCHEMBL7158594 | 0.65 | — | — | |
| SCHEMBL12778667 | 0.65 | HRH1 (0.39) | HRH1HRH4FDPSBAZ2BTSHR | |
| SCHEMBL28041192 | 0.65 | — | — | |
| SCHEMBL3434664 | 0.64 | HCAR2 (0.47) | LMNAGLAALDH1A1F2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478497-B | Arylalkyl acid GLP-1 receptor agonists and uses thereof | 杭州中美华东制药有限公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-0563238-A4 | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORP (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0563238-A1 | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992010189-A1 | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-06-25 | — | — | WO | disclosed |