Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28057548 | 0.75 | CYP2C19 (0.44) | SRD5A2CYP2C19HSD17B10KDM5AKDM4C | |
| SCHEMBL28057544 | 0.73 | SRD5A2 (0.42) | SRD5A2MAOBMEN1KMT2ABACE1 | |
| SCHEMBL839809 | 0.66 | KIF11 (0.59) | SRD5A2MAOBMEN1KMT2ABACE1 | |
| SCHEMBL2610303 | 0.66 | KMT2A (0.70) | SRD5A2MAOBMEN1KMT2A | |
| SCHEMBL13542853 | 0.66 | ALDH1A1 (0.58) | SRD5A2MAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL15735903 | 0.65 | MAOB (0.47) | SRD5A2MAOBMEN1KMT2ABACE1 | |
| SCHEMBL29906422 | 0.65 | ALDH1A1 (0.48) | SRD5A2MAOBMEN1KMT2ABACE1 | |
| SCHEMBL28768532 | 0.65 | MAOB (0.44) | SRD5A2MAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL26982493 | 0.65 | ALDH1A1 (0.48) | SRD5A2MAOBMEN1KMT2ABACE1 | |
| SCHEMBL29026435 | 0.65 | MAPT (0.49) | MAOBMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431416-A | 4-alkynyl imidazole derivative and medicine comprising same as active ingredient | KAKEN PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |