Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778693 | 0.72 | SMN1; SMN2 (0.61) | LMNASMN1; SMN2EPHX2FDFT1ALDH1A1 | |
| SCHEMBL28057909 | 0.72 | KDM4E (0.38) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17352418 | 0.70 | LMNA (0.55) | LMNASMN1; SMN2EPHX2FDFT1ALDH1A1 | |
| SCHEMBL10151333 | 0.70 | LMNA (0.55) | LMNASMN1; SMN2EPHX2FDFT1ALDH1A1 | |
| SCHEMBL5263064 | 0.70 | LMNA (0.55) | LMNASMN1; SMN2EPHX2FDFT1ALDH1A1 | |
| SCHEMBL28057902 | 0.69 | KDM4E (0.46) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28058013 | 0.69 | EPHX2 (0.41) | EPHX2ALDH1A1 | |
| SCHEMBL13724865 | 0.68 | KDM4E (0.45) | SMN1; SMN2EPHX2ALDH1A1KDM4E | |
| SCHEMBL17352352 | 0.67 | EPHX2 (0.58) | LMNASMN1; SMN2EPHX2ALDH1A1L3MBTL1 | |
| SCHEMBL13330072 | 0.67 | LMNA (0.47) | LMNASMN1; SMN2EPHX2FDFT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101597196-B | Improved drug candidate and preparation method thereof | JIYAKETA CO., LTD. (CH) | 2016-05-04 | — | — | CN | disclosed |