Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058138 | 0.89 | TDP1 (0.71) | TDP1ALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL16469850 | 0.82 | KDM4E (0.49) | ALDH1A1LMNASMN1; SMN2MAPTALOX15 | |
| SCHEMBL16470520 | 0.82 | NHERF1 (0.51) | ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL24312124 | 0.82 | FFAR4 (0.54) | ALDH1A1PKMKMT2AMEN1ALOX15 | |
| SCHEMBL16469750 | 0.81 | CA12 (0.51) | TDP1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15359747 | 0.81 | NPC1 (0.51) | TDP1ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL16489168 | 0.80 | KDM4E (0.47) | ALDH1A1LMNASMN1; SMN2MAPTALOX15 | |
| SCHEMBL16469306 | 0.80 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL15360019 | 0.79 | MEN1 (0.49) | ALDH1A1LMNASMN1; SMN2PKMKMT2A | |
| SCHEMBL16469731 | 0.77 | LMNA (0.58) | ALDH1A1LMNASMN1; SMN2PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395297-B | Sulfonamide derivatives and pharmaceutical use thereof | AJINOMOTO CO.,INC. (JP) | 2016-05-04 | — | — | CN | disclosed |