SCHEMBL28058459

SCHEMBL28058459

Cc1cnn(C)c1NC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
LPAR1 Q92633 2/20 0.38
SMN1; SMN2 Q16637 4/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
AHR P35869 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HTT P42858 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
TP53 P04637 1/20 0.33
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33
GRIA4 P48058 1/20 0.33
P2RX7 Q99572 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20540314 0.82 MEN1 (0.39) MEN1KMT2ALPAR1SMN1; SMN2NPC1
SCHEMBL26789504 0.82 MAPT (0.40) SMN1; SMN2NPC1RAB9AALDH1A1HTT
SCHEMBL20539629 0.81 MEN1 (0.38) MEN1KMT2ALPAR1SMN1; SMN2NPC1
SCHEMBL3772649 0.81 MEN1 (0.59) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL15880434 0.81 MEN1 (0.38) MEN1KMT2ALPAR1SMN1; SMN2NPC1
SCHEMBL10937844 0.80 ALDH1A1 (0.51) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL20540428 0.78 ALDH1A1 (0.50) MEN1KMT2ALPAR1SMN1; SMN2NPC1
SCHEMBL20540355 0.77 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1HTTHPGDTP53
SCHEMBL15882151 0.77 SMN1; SMN2 (0.40) MEN1KMT2ALPAR1SMN1; SMN2NPC1
SCHEMBL14098867 0.76 KMT2A (0.52) MEN1KMT2ASMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105359385-A Member for dynamo-electric machine, dynamo-electric machine, and resin composition HITACHI AUTOMOTIVE SYSTEMS LTD 2016-02-24 CN disclosed