Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058459 | 0.81 | MEN1 (0.40) | MEN1KMT2ALPAR1SMN1; SMN2NPC1 | |
| SCHEMBL20540314 | 0.79 | MEN1 (0.39) | MEN1KMT2ALPAR1SMN1; SMN2NPC1 | |
| SCHEMBL20540428 | 0.79 | ALDH1A1 (0.50) | MEN1KMT2ALPAR1SMN1; SMN2NPC1 | |
| SCHEMBL3772649 | 0.78 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15880434 | 0.78 | MEN1 (0.38) | MEN1KMT2ALPAR1SMN1; SMN2NPC1 | |
| SCHEMBL15882151 | 0.77 | SMN1; SMN2 (0.40) | MEN1KMT2ALPAR1SMN1; SMN2NPC1 | |
| SCHEMBL21164256 | 0.77 | GSK3B (0.39) | MEN1KMT2ALPAR1NPC1RAB9A | |
| SCHEMBL12988476 | 0.76 | LPAR1 (0.50) | LPAR1 | |
| SCHEMBL5497757 | 0.74 | BRD9 (0.36) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20540355 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1POLBHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | SANDOZ AG (CH) | 2019-07-16 | — | — | US | disclosed |
| EP-3313821-B1 | PROCESS FOR THE PREPARATION OF CARBAMOYLAMINO PYRAZOLE DERIVATIVES | SANDOZ AG (CH) | 2019-04-10 | — | — | EP | disclosed |
| US-20180305319-A1 | Process for the Preparation of Carbamoylamino Pyrazole Derivatives | SANDOZ AG (CH) | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | PAICS, PPOX, DDC | MEN1 1136/4885KMT2A 448/4885LPAR1 4217/4885 |
| US-20180305319-A1 | Process for the Preparation of Carbamoylamino Pyrazole Derivatives | PAICS, PPOX, DDC | MEN1 1136/4885KMT2A 448/4885LPAR1 4217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.