Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15882151 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1TP53HPGDCYP1A2 | |
| SCHEMBL8997219 | 0.82 | PTGS1 (0.58) | SMN1; SMN2ALDH1A1TP53HPGDCYP1A2 | |
| SCHEMBL8997215 | 0.81 | PTGS1 (0.55) | SMN1; SMN2ALDH1A1TP53HPGDCYP1A2 | |
| SCHEMBL8997249 | 0.77 | CYP1A2 (0.56) | SMN1; SMN2ALDH1A1TP53HPGDCYP1A2 | |
| SCHEMBL29174925 | 0.77 | CYP1A2 (0.46) | SMN1; SMN2ALDH1A1TP53HPGDCYP1A2 | |
| SCHEMBL28058459 | 0.77 | MEN1 (0.40) | SMN1; SMN2ALDH1A1TP53HPGDHTT | |
| SCHEMBL20540314 | 0.75 | MEN1 (0.39) | SMN1; SMN2ALDH1A1HPGDHTT | |
| SCHEMBL8554538 | 0.75 | PTGS1 (0.54) | SMN1; SMN2ALDH1A1TP53LMNATSHR | |
| SCHEMBL20539629 | 0.74 | MEN1 (0.38) | SMN1; SMN2ALDH1A1TP53HPGDHTT | |
| SCHEMBL3772649 | 0.74 | MEN1 (0.59) | SMN1; SMN2CYP1A2CYP2C19HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | SANDOZ AG (CH) | 2019-07-16 | — | — | US | disclosed |
| EP-3313821-B1 | PROCESS FOR THE PREPARATION OF CARBAMOYLAMINO PYRAZOLE DERIVATIVES | SANDOZ AG (CH) | 2019-04-10 | — | — | EP | disclosed |
| US-20180305319-A1 | Process for the Preparation of Carbamoylamino Pyrazole Derivatives | SANDOZ AG (CH) | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | PAICS, PPOX, DDC | SMN1; SMN2 4257/4885ALDH1A1 2213/4885TP53 770/4885 |
| US-20180305319-A1 | Process for the Preparation of Carbamoylamino Pyrazole Derivatives | PAICS, PPOX, DDC | SMN1; SMN2 4257/4885ALDH1A1 2213/4885TP53 770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.