Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15998476 | 0.82 | ALDH1A1 (0.46) | ALDH1A1POLBPDE4BNPC1RAB9A | |
| SCHEMBL18343692 | 0.81 | ALDH1A1 (0.46) | ALDH1A1POLBPDE4BNPC1RAB9A | |
| SCHEMBL20539629 | 0.79 | MEN1 (0.38) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20540560 | 0.79 | ALDH1A1 (0.45) | ALDH1A1POLBRAB9ATYK2LPAR1 | |
| SCHEMBL28058459 | 0.78 | MEN1 (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12258916 | 0.78 | ALDH1A1 (0.43) | ALDH1A1POLBPDE4BRIPK2TYK2 | |
| SCHEMBL20540314 | 0.77 | MEN1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL18145266 | 0.76 | ALDH1A1 (0.46) | ALDH1A1POLBPDE4BNPC1RAB9A | |
| SCHEMBL6397435 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3772649 | 0.75 | MEN1 (0.59) | POLBNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | SANDOZ AG (CH) | 2019-07-16 | — | — | US | disclosed |
| EP-3313821-B1 | PROCESS FOR THE PREPARATION OF CARBAMOYLAMINO PYRAZOLE DERIVATIVES | SANDOZ AG (CH) | 2019-04-10 | — | — | EP | disclosed |
| US-20180305319-A1 | Process for the Preparation of Carbamoylamino Pyrazole Derivatives | SANDOZ AG (CH) | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | PAICS, PPOX, DDC | ALDH1A1 2213/4885POLB 577/4885PDE4B 884/4885 |
| US-20180305319-A1 | Process for the Preparation of Carbamoylamino Pyrazole Derivatives | PAICS, PPOX, DDC | ALDH1A1 2213/4885POLB 577/4885PDE4B 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.