Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | NEK2 | P51955 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14727965 | 0.91 | ACLY (0.35) | SSTR5CA1CA2SGK1CAMKK2 | |
| SCHEMBL14723349 | 0.88 | RXRB (0.43) | PDK2CA1CA2RXRARXRB | |
| SCHEMBL14723352 | 0.88 | RXRB (0.43) | PDK2CA1CA2RXRARXRB | |
| SCHEMBL1795774 | 0.83 | ACLY (0.33) | SSTR5CA1CA2DCLRE1B | |
| SCHEMBL1798784 | 0.82 | GPR52 (0.35) | PDK2SSTR5CA1CA2 | |
| SCHEMBL3457034 | 0.82 | ACLY (0.35) | PDK2SSTR5CA1CA2DCLRE1B | |
| SCHEMBL31589793 | 0.82 | RXRB (0.42) | PDK2FABP4RXRARXRB | |
| SCHEMBL1801082 | 0.82 | ACLY (0.33) | SSTR5CA1CA2DCLRE1B | |
| SCHEMBL20548328 | 0.82 | PDK2 (0.40) | PDK2CA1CA2FABP4RXRA | |
| SCHEMBL20547572 | 0.82 | PDK2 (0.40) | PDK2CA1CA2FABP4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104066330-B | Isoxazoline derivatives for controlling ectoparasites | ANACOR PHARMACEUTICALS, INC. (US) | 2016-05-18 | — | — | CN | disclosed |