Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059095 | 0.88 | MAPK14 (0.58) | MAPTMEN1KMT2AMAPK14ALDH1A1 | |
| SCHEMBL28059091 | 0.87 | MAPK14 (0.53) | MAPTMAPK14KDM4EMAPK13MAPK12 | |
| SCHEMBL28059008 | 0.85 | MAPK14 (0.54) | MAPTMEN1KMT2AMAPK14ALDH1A1 | |
| SCHEMBL28059004 | 0.85 | MAPK14 (0.55) | MAPTMEN1KMT2AMAPK14ALDH1A1 | |
| SCHEMBL30643204 | 0.79 | GRM5 (0.62) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28059099 | 0.74 | MAPK14 (0.48) | MAPTMEN1KMT2AMAPK14ALDH1A1 | |
| SCHEMBL5051520 | 0.74 | GRM4 (0.51) | MAPTMEN1KMT2AMAPK14ALDH1A1 | |
| SCHEMBL17732529 | 0.74 | LMNA (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4201209 | 0.73 | RAB9A (0.59) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4899528 | 0.73 | RAB9A (0.53) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585565-A | 2-phenylamino-4-thiazolyl pyridine derivatives, preparing method thereof, pharmaceutical compositions of the derivatives and uses of the derivatives | INST MATERIA MEDICA CAMS | 2016-05-18 | — | — | CN | claimed |
| CN-105585565-A | 2-phenylamino-4-thiazolyl pyridine derivatives, preparing method thereof, pharmaceutical compositions of the derivatives and uses of the derivatives | INST MATERIA MEDICA CAMS | 2016-05-18 | — | — | CN | disclosed |