Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19512230 | 0.88 | MCL1 (0.46) | PTGER4PARP1HCAR3ALDH1A1CSNK2A2 | |
| SCHEMBL2935768 | 0.77 | SLC22A12 (0.58) | PTGER4HCAR3ALDH1A1CNR2MCL1 | |
| SCHEMBL14448731 | 0.77 | PPARG (0.43) | PARP1ALDH1A1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4506807 | 0.75 | PPARG (0.61) | ALDH1A1KMT2APPARG | |
| SCHEMBL28092003 | 0.74 | PPARG (0.54) | ALDH1A1KMT2ACNR2POLBRAD52 | |
| SCHEMBL12523931 | 0.73 | MCL1 (0.47) | HCAR3ALDH1A1CNR2MCL1 | |
| SCHEMBL18941207 | 0.72 | RAD52 (0.61) | PTGER4ALDH1A1CSNK2A1KMT2ACNR2 | |
| SCHEMBL18966441 | 0.71 | HPGD (0.66) | HCAR3ALDH1A1KMT2ACNR2POLB | |
| SCHEMBL2930757 | 0.71 | MCL1 (0.67) | HCAR3ALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL13578013 | 0.71 | SLC22A12 (0.61) | PTGER4HCAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240644-A1 | MORPHOLINE DERIVATIVE | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240644-A1 | MORPHOLINE DERIVATIVE | REN, AGTR1, AGTR2 | PTGER4 873/4885PARP1 3636/4885HCAR3 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.