Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20744106 | 0.89 | HSD17B10 (0.30) | — | |
| SCHEMBL21856103 | 0.89 | OPRM1 (0.38) | OPRM1KDM4EKMT2A | |
| SCHEMBL14831137 | 0.86 | CYP2D6 (0.32) | OPRM1KDM4EKMT2A | |
| SCHEMBL22499953 | 0.83 | KDM4E (0.32) | KDM4EKMT2A | |
| SCHEMBL23121017 | 0.81 | SLC6A2 (0.32) | OPRM1 | |
| SCHEMBL20908043 | 0.78 | — | — | |
| SCHEMBL3942864 | 0.77 | P2RX7 (0.34) | KMT2A | |
| SCHEMBL13738101 | 0.77 | P2RX7 (0.34) | KMT2A | |
| SCHEMBL5167704 | 0.75 | SMN1; SMN2 (0.39) | KMT2A | |
| SCHEMBL4725793 | 0.75 | KDM4E (0.34) | OPRM1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492377-B | As the triazolopyridine compounds of PIM kinase inhibitor | ARRAY BIOPHARMA INC. (US) | 2016-04-20 | — | — | CN | disclosed |