Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.30 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060908 | 1.00 | CPB2 (0.39) | CPB2GABRR1HTTENPEPADRA1A | |
| SCHEMBL6894525 | 0.80 | HTT (0.47) | CPB2HTTADRA1ACHRM1AKR1A1 | |
| SCHEMBL4457494 | 0.80 | HTT (0.47) | CPB2HTTADRA1ACHRM1AKR1A1 | |
| SCHEMBL11506347 | 0.79 | CPB2 (0.50) | CPB2GABRR1ENPEPHDAC1HDAC2 | |
| SCHEMBL233153 | 0.76 | TDP1 (0.40) | TDP1TSHRALDH1A1KMT2A | |
| SCHEMBL233154 | 0.76 | TDP1 (0.40) | TDP1TSHRALDH1A1KMT2A | |
| SCHEMBL10724840 | 0.74 | CPB1 (0.39) | TDP1LMNATSHRALDH1A1KMT2A | |
| SCHEMBL6889610 | 0.74 | CHRM1 (0.46) | CPB2HTTADRA1ACHRM1AKR1A1 | |
| SCHEMBL489096 | 0.74 | RNPEP (0.43) | ADRA1ATDP1LMNACACNA2D1CACNB3 | |
| SCHEMBL1258031 | 0.74 | RNPEP (0.43) | ADRA1ATDP1LMNACACNA2D1CACNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585544-A | Trans-substituted alkene derivative, medicine composition containing same and medical application of trans-substituted alkene derivative | XIXI HOSPITAL OF HANGZHOU | 2016-05-18 | — | — | CN | disclosed |