Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | USP7 | Q93009 | 4/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28135252 | 0.82 | ADORA2A (0.52) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7171237 | 0.75 | POLB (0.50) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL3509699 | 0.74 | CYP17A1 (0.35) | — | |
| SCHEMBL27941436 | 0.73 | GSK3A (0.42) | MEN1KMT2AMAPTRAB9AHPGD | |
| SCHEMBL13294782 | 0.73 | MKNK1 (0.56) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL13295147 | 0.72 | HPGDS (0.48) | MEN1KMT2A | |
| SCHEMBL210678 | 0.71 | MEN1 (0.66) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL12821368 | 0.71 | HSP90AA1 (0.66) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL27115085 | 0.71 | MEN1 (0.66) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL9130502 | 0.70 | RAB9A (0.44) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103649073-B | 17 α-hydroxylase/C 17,20-lyase inhibitor | NOVARTIS AG (CH) | 2016-04-13 | — | — | CN | disclosed |