Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 8/20 | 0.61 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4196912 | 0.96 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2DNM1KCNH2 | |
| Water SCHEMBL10628780 | 0.92 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2KCNH2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL465040 | 0.92 | BDKRB2 (0.71) | BDKRB2CSNK1ECNR2KCNH2 | |
| Bromide SCHEMBL5086868 | 0.92 | BDKRB2 (0.60) | BDKRB2CSNK1ECNR2DNM1KCNH2 | |
| Bromide SCHEMBL5087857 | 0.92 | BDKRB2 (0.60) | BDKRB2CSNK1ECNR2DNM1KCNH2 | |
| Iodide SCHEMBL5092861 | 0.92 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2KCNH2SIGMAR1 | |
| Bromide SCHEMBL5087978 | 0.90 | BDKRB2 (0.72) | BDKRB2CSNK1ECNR2DNM1KCNH2 | |
| Bromide SCHEMBL5092800 | 0.89 | BDKRB2 (0.70) | BDKRB2CSNK1EDNM1KCNH2 | |
| Bromide SCHEMBL20163257 | 0.89 | BDKRB2 (0.70) | BDKRB2CSNK1EDNM1KCNH2 | |
| Bromide SCHEMBL624280 | 0.89 | BDKRB2 (0.70) | BDKRB2CSNK1EDNM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109312054-A | Fibre reinforced composites two-liquid type composition epoxy resin and fibre reinforced composites | 东丽株式会社 | 2019-02-05 | — | — | CN | disclosed |
| CN-105481639-B | A kind of preparation method of biphenyl compound | 阜阳欣奕华材料科技有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-108948064-A | A kind of eribulin intermediate and preparation method thereof | 上海时莱生物技术有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-107406607-A | Fiber reinforced composite material two-component-type composition epoxy resin and fiber reinforced composite material | 东丽株式会社 | 2017-11-28 | — | — | CN | disclosed |
| CN-102238983-B | Benzotropolone derivatives is as UV absorbent and the purposes of antioxidant and the purposes in sun-screening agent and/or cosmetic composition thereof | 巴斯夫欧洲公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-102977146-B | A kind of synthetic method of adenine derivative | XINGHU BIOTECH CO., LTD., ZHAOQING CITY, GUANGDONG PROV. (CN) | 2016-04-20 | — | — | CN | disclosed |
| CN-105481639-A | Method for preparing biphenyl compound | FUYANG XINYIHUA MAT TECH CO LTD | 2016-04-13 | — | — | CN | disclosed |