Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 8/20 | 0.66 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5088116 | 0.96 | BDKRB2 (0.60) | BDKRB2CSNK1ECNR2TP53KCNH2 | |
| Iodide SCHEMBL5086712 | 0.96 | BDKRB2 (0.60) | BDKRB2CSNK1ECNR2TP53KCNH2 | |
| Water SCHEMBL10628780 | 0.96 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2TP53KCNH2 | |
| Hydrochloric Acid SCHEMBL465040 | 0.96 | BDKRB2 (0.71) | BDKRB2CSNK1ECNR2TP53KCNH2 | |
| Bromide SCHEMBL4196912 | 0.96 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2TP53KCNH2 | |
| Iodide SCHEMBL5085117 | 0.94 | BDKRB2 (0.67) | BDKRB2CSNK1ECNR2KCNH2SIGMAR1 | |
| Bromide SCHEMBL28061319 | 0.92 | BDKRB2 (0.61) | BDKRB2CSNK1ECNR2KCNH2SIGMAR1 | |
| Iodide SCHEMBL5085386 | 0.92 | BDKRB2 (0.65) | BDKRB2CSNK1ETP53KCNH2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5091629 | 0.92 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2TP53KCNH2 | |
| Bromide SCHEMBL5087857 | 0.92 | BDKRB2 (0.60) | BDKRB2CSNK1ECNR2TP53KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| US-6806387-B2 | A STARTING MATERIAL FOR VITAMIN A DERIVATIVES AND VARIOUS TERPENE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-10-19 | — | — | US | disclosed |
| EP-1426357-A1 | PROCESS FOR PREPARATION OF ALLYL SULFONE DERIVATIVES AND INTERMEDIATES FOR THE PREPARATION | Sumitomo Chemical Company, Limited (JP) | 2004-06-09 | — | — | EP | disclosed |
| US-20040054233-A1 | Process for preparation of allyl sulfone derivatives and intermediates for the preparation | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054233-A1 | Process for preparation of allyl sulfone derivatives and intermediates for the preparation | ARSA, SULT1A1, SULT2A1 | BDKRB2 1703/4885CSNK1E 94/4885CNR2 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.