Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 8/20 | 0.71 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5092861 | 0.96 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2TP53SMN1; SMN2 | |
| Bromide SCHEMBL4196912 | 0.96 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2TP53KCNH2 | |
| Water SCHEMBL10628780 | 0.96 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5091319 | 0.96 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2TP53MEN1 | |
| Hydrochloric Acid SCHEMBL5091629 | 0.96 | BDKRB2 (0.66) | BDKRB2CSNK1ECNR2TP53MEN1 | |
| Hydrochloric Acid SCHEMBL9342631 | 0.94 | BDKRB2 (0.68) | BDKRB2CSNK1ETP53MEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL5087534 | 0.94 | BDKRB2 (0.72) | BDKRB2CSNK1ETP53MEN1MAPK1 | |
| Bromide SCHEMBL28061319 | 0.92 | BDKRB2 (0.61) | BDKRB2CSNK1ECNR2KCNH2 | |
| Hydrochloric Acid SCHEMBL624934 | 0.92 | BDKRB2 (0.70) | BDKRB2CSNK1ETP53MEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL5088466 | 0.92 | BDKRB2 (0.70) | BDKRB2CSNK1ETP53MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1042 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060043-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC (US) | 2025-11-26 | — | — | EP | claimed |
| US-20240122179-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | CORTEVA AGRISCIENCE LLC (US) | 2024-04-18 | — | — | US | claimed |
| US-11859074-B2 | Curable fluoroelastomer composition | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-01-02 | — | — | US | claimed |
| CN-117088746-A | Preparation method of parylene series products and parylene series products | 苏州亚科科技股份有限公司 | 2023-11-21 | — | — | CN | claimed |
| EP-4099814-A1 | METHOD FOR IMPROVING THE STABILITY OF A CULTIVATED PLANT | Omnicult Farmconcept GmbH (DE) | 2022-12-14 | — | — | EP | claimed |
| WO-2022170075-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | CORTEVA AGRISCIENCE LLC (US) | 2022-08-11 | — | — | WO | claimed |
| US-20210392890-A1 | COMPOSITIONS COMPRISING PYRIDINE CARBOXYLATE HERBICIDES AND PLANT GROWTH REGULATORS | CORTEVA AGRISCIENCE LLC (US) | 2021-12-23 | — | — | US | claimed |
| US-20210292533-A1 | CURABLE FLUOROELASTOMER COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY | 2021-09-23 | — | — | US | claimed |
| EP-3876734-A1 | COMPOSITIONS COMPRISING PYRIDINE CARBOXYLATE HERBICIDES AND PLANT GROWTH REGULATORS | Corteva Agriscience LLC (US) | 2021-09-15 | — | — | EP | claimed |
| CN-113292921-A | Composite insulator coating, preparation method and spraying process | 广东电网有限责任公司 | 2021-08-24 | — | — | CN | claimed |
| EP-1347012-A2 | Curable Fluoroelastomers | Solvay Solexis S.p.A. (IT) | 2003-09-24 | — | — | EP | claimed |
| WO-2000062792-A2 | COMPOSITIONS AND METHODS FOR CONTROLLING PESTS | INSECT BIOTECHNOLOGY, INC. (US) | 2000-10-26 | — | — | WO | claimed |
| EP-0561033-B1 | Polymeric phoshonium salts providing enhanced chemiluminescence from 1,2-dioxetanes, and their use. | LUMIGEN INC (US) | 2000-03-15 | — | — | EP | claimed |
| EP-0827496-A1 | CATALIC ENANTIOSELECTIVE SYNTHESIS OF A SPIRO-FUSED AZETIDINONE | SCHERING CORPORATION (US) | 1998-03-11 | — | — | EP | claimed |
| WO-1996027587-A1 | CATALIC ENANTIOSELECTIVE SYNTHESIS OF A SPIRO-FUSED AZETIDINONE | SCHERING CORPORATION (US) | 1996-09-12 | — | — | WO | claimed |
| US-5393469-A | Triggering dioxetane with activating agents consisting of acids, bases, salts, enzymes, inorganic or organic catalysts and electron donors; used for immunoassay and nucleic acid assay | LUMIGEN, INC. (US) | 1995-02-28 | — | — | US | claimed |
| US-5371143-A | Polymer blend composition of fluorinated elastomers, thermoplastic polymers and thermoplastics elastomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-06 | — | — | US | claimed |
| EP-0561033-A1 | Polymeric phoshonium salts providng enhanced chemiluminescence from 1,2-dioxetanes | LUMIGEN, INC. (US) | 1993-09-22 | — | — | EP | claimed |
| US-4912171-A | Blend of addition polymer, polyhydroxy compound, organo-onium compound and acid acceptor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-03-27 | — | — | US | claimed |
| US-4882390-A | AND POLYHYDROXY COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210392890-A1 | COMPOSITIONS COMPRISING PYRIDINE CARBOXYLATE HERBICIDES AND PLANT GROWTH REGULATORS | GRHPR, PPARG, PGR | BDKRB2 4169/4885CSNK1E 3442/4885CNR2 416/4885 |
| US-20240122179-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | DDT, HACL2, ALAD | BDKRB2 3897/4885CSNK1E 4555/4885CNR2 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.