Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | EGFR | P00533 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | BACE1 | P56817 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Erbstatin SCHEMBL9320673 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAEGFRKDM4E | |
| Erbstatin SCHEMBL9320680 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9322706 | 0.85 | EGFR (0.74) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9322697 | 0.85 | EGFR (0.74) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9320662 | 0.82 | KDM4E (0.70) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9320670 | 0.82 | KDM4E (0.70) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL10413034 | 0.78 | MAPT (0.64) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9320061 | 0.77 | MAPT (0.62) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9320066 | 0.77 | MAPT (0.62) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9730856 | 0.75 | MAPT (0.60) | ALDH1A1MAPTGAAEGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251569-A1 | TREATMENT AND PREVENTION OF DISEASE MEDIATED BY WWP2 | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2022-08-11 | — | — | US | disclosed |
| CN-114641571-A | Treatment and prevention of WWP2 mediated diseases | 新加坡国立大学 | 2022-06-17 | — | — | CN | disclosed |
| EP-3983544-A1 | TREATMENT AND PREVENTION OF DISEASE MEDIATED BY WWP2 | National University of Singapore (SG) | 2022-04-20 | — | — | EP | disclosed |
| CN-105385011-A | TPV composition and automobile anti-collision strip | Jiaxing boer plastic co ltd | 2016-03-09 | — | — | CN | disclosed |