Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | EGFR | P00533 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | BACE1 | P56817 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Erbstatin SCHEMBL9320680 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAEGFRKDM4E | |
| Erbstatin SCHEMBL28061341 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9322706 | 0.85 | EGFR (0.74) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9322697 | 0.85 | EGFR (0.74) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9320662 | 0.82 | KDM4E (0.70) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9320670 | 0.82 | KDM4E (0.70) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL10413034 | 0.78 | MAPT (0.64) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9320061 | 0.77 | MAPT (0.62) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9320066 | 0.77 | MAPT (0.62) | ALDH1A1MAPTGAAEGFRKDM4E | |
| SCHEMBL9730856 | 0.75 | MAPT (0.60) | ALDH1A1MAPTGAAEGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4401787-B1 | VECTORS TARGETING BETA-D-N-ACETYLGLUCOSAMINIDASE | CENTRE NAT RECH SCIENT (FR) | 2025-11-05 | — | — | EP | disclosed |
| WO-2025068340-A1 | METHOD TO PREDICT AML OUTCOME | Institut National de la Santé et de la Recherche Médicale (FR) | 2025-04-03 | — | — | WO | disclosed |
| EP-4401787-A1 | VECTORS TARGETING BETA-D-N-ACETYLGLUCOSAMINIDASE | Centre National de la Recherche Scientifique (FR) | 2024-07-24 | — | — | EP | disclosed |
| WO-2023041531-A1 | VECTORS TARGETING BETA-D-N-ACETYLGLUCOSAMINIDASE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-03-23 | — | — | WO | disclosed |
| CN-105385011-B | A kind of TPV compositions and automobile collision preventing billot | 嘉兴市博尔塑胶有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-105385011-A | TPV composition and automobile anti-collision strip | Jiaxing boer plastic co ltd | 2016-03-09 | — | — | CN | disclosed |
| EP-2846788-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF PAIN | Akron Molecules AG (AT) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013167743-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF PAIN | AKRON MOLECULES GMBH (AT) | 2013-11-14 | — | — | WO | disclosed |
| EP-1404659-B1 | 4-ARYL QUINOLS AND ANALOGS THEREOF AS THERAPEUTIC AGENTS | CANCER REC TECH LTD (GB) | 2010-02-10 | — | — | EP | disclosed |
| EP-1572197-B1 | 4- 1- (SULFONYL) -1H-INDOL-2-YL)-4- (HYDROXY) -CYCLOHEXA-2,5-DIENONE COMPOUNDS AND ANALOGS THEREOF AS THERAPEUTIC AGENTS | CANCER REC TECH LTD (GB) | 2009-07-29 | — | — | EP | disclosed |
| US-7307099-B2 | 4-(1-(sulfonyl)-1h-indol-2-yl)-4-(hydroxy)-cyclohexa-2,5-dienone compounds and analogs thereof as therapeutic agents | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-12-11 | — | — | US | disclosed |
| US-7307099-B2 | 4-(1-(sulfonyl)-1h-indol-2-yl)-4-(hydroxy)-cyclohexa-2,5-dienone compounds and analogs thereof as therapeutic agents | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-12-11 | — | — | US | disclosed |
| EP-0440887-B1 | Improvement in the total synthesis of Erbstatin analogs | ERBA CARLO SPA (IT) | 1994-01-26 | — | — | EP | disclosed |
| US-5130472-A | TOTAL SYNTHESIS OF ERBSTATIN ANALOGS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-07-14 | — | — | US | disclosed |
| EP-0440887-A1 | Improvement in the total synthesis of Erbstatin analogs | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-08-14 | — | — | EP | disclosed |
| US-4925877-A | ANTITUMOR AGENTS, BACTERICIDES, ENZYME INHIBITOR | ZAIDANHOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0238868-A2 | New physiologically active substance erbstatin analogous compounds | Zaidanhojin Biseibutsu Kagaku Kenkyukai (JP) | 1987-09-30 | — | — | EP | disclosed |