SCHEMBL28061366

SCHEMBL28061366

S=C=Nc1cccnc1C1CNCCO1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.40
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
HTR1A P08908 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28666083 0.76 DRD2 (0.50) DRD2DRD3
SCHEMBL27816652 0.75 DRD2 (0.42) DRD2DRD3HTR1A
SCHEMBL28105993 0.75 DRD2 (0.42) DRD2DRD3
SCHEMBL28860435 0.74 DRD2 (0.41) DRD2DRD3HTR1A
SCHEMBL28029236 0.73 ADRA2C (0.52) HTR1A
SCHEMBL1665692 0.72 DRD2 (0.40) DRD2DRD3HTR1A
SCHEMBL28257239 0.72 DRD2 (0.43) DRD2DRD3HTR1A
SCHEMBL29034249 0.72 DRD2 (0.37) DRD2DRD3
SCHEMBL28010292 0.71 DRD2 (0.42) DRD2DRD3
SCHEMBL8152385 0.71 HTR7 (0.42) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105385011-A TPV composition and automobile anti-collision strip Jiaxing boer plastic co ltd 2016-03-09 CN disclosed