SCHEMBL28061374

SCHEMBL28061374

C=CNC(=O)c1ccc(N)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.53
POLB P06746 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
PKM P14618 1/20 0.53
APEX1 P27695 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
HIF1A Q16665 1/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.45
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
CYP2C19 P33261 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
PTGS1 P23219 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9794350 0.83 LMNA (0.57) LMNAPOLBMEN1KMT2APKM
SCHEMBL27668460 0.81 LMNA (0.55) LMNAPOLBMEN1KMT2APKM
SCHEMBL6594424 0.79 HPGD (0.61) LMNAPOLBMEN1KMT2APKM
SCHEMBL22915186 0.79 MEN1 (0.50) POLBMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL4924405 0.79 ALDH1A1 (0.55) LMNAPOLBMEN1KMT2ATDP1
SCHEMBL31030766 0.79 OGG1 (0.55) LMNAPOLBMEN1KMT2ATDP1
SCHEMBL497521 0.78 NPC1 (0.57) LMNAPOLBMEN1KMT2ATDP1
SCHEMBL18464180 0.78 ALDH1A1 (0.52) LMNAMAPTKDM4ESMN1; SMN2NPC1
SCHEMBL31030711 0.76 HDAC1 (0.60) LMNAPOLBMEN1KMT2AMAPT
SCHEMBL31030773 0.76 RAB9A (0.60) LMNAPOLBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109608919-B Efficient environment-friendly UV-moisture dual-curing three-proofing paint for flexible circuit board 深圳市亿铖达工业有限公司 2020-10-27 CN claimed
CN-109608919-B Efficient environment-friendly UV-moisture dual-curing three-proofing paint for flexible circuit board 深圳市亿铖达工业有限公司 2020-10-27 CN disclosed
CN-109608919-A A kind of double solidification flexible circuit board three-proofing coatings of efficient and environment-friendly type UV- moisture 深圳市亿铖达工业有限公司 2019-04-12 CN disclosed
CN-105385011-A TPV composition and automobile anti-collision strip Jiaxing boer plastic co ltd 2016-03-09 CN disclosed