Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893057 | 0.88 | PTPN1 (0.44) | CCNA2CDK2CCNA1ACACBCYP11B2 | |
| SCHEMBL30697767 | 0.75 | FPR2 (0.47) | CCNA2CDK2CCNA1TSHRPTPN1 | |
| SCHEMBL5104476 | 0.74 | USP30 (0.51) | CCNA2CDK2CCNA1TSHRPTPN1 | |
| SCHEMBL891655 | 0.73 | TSHR (0.47) | PDE4BTSHRPTPN1USP30ALDH1A1 | |
| SCHEMBL20525295 | 0.72 | CCNA2 (0.42) | CCNA2CDK2CCNA1 | |
| SCHEMBL29009170 | 0.71 | ALDH1A1 (0.53) | CCNA2CDK2CCNA1MCHR1ROCK2 | |
| SCHEMBL4465548 | 0.70 | ALDH1A1 (0.50) | CCNA2CDK2CCNA1TSHRALDH1A1 | |
| SCHEMBL27081930 | 0.70 | CCNA2 (0.44) | CCNA2CDK2CCNA1PTPN1USP30 | |
| SCHEMBL4477802 | 0.69 | F10 (0.42) | CCNA2CDK2CCNA1PTPN1USP30 | |
| SCHEMBL30697766 | 0.67 | MAPT (0.48) | TSHRALDH1A1HSP90AA1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803252-B | Be used for the treatment of indole amides derivative and the related compound thereof of neurodegenerative disorders | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2016-05-25 | — | — | CN | disclosed |