Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892790 | 0.87 | PTPN1 (0.49) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL30697767 | 0.81 | FPR2 (0.47) | MAPTMEN1KMT2ATDP1CCNA2 | |
| SCHEMBL5104476 | 0.80 | USP30 (0.51) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL14301511 | 0.79 | ROCK2 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27081930 | 0.79 | CCNA2 (0.44) | ALDH1A1KMT2AROCK2CCNA2CDK2 | |
| SCHEMBL19327276 | 0.77 | ROCK2 (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL22365570 | 0.77 | ROCK2 (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL3504973 | 0.76 | NPC1 (0.63) | KMT2APOLB | |
| SCHEMBL3504969 | 0.76 | NPC1 (0.63) | KMT2APOLB | |
| SCHEMBL4465548 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTMAPK1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |