Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308869 | 0.86 | PTPN1 (0.59) | USP30PTPN1MEN1KMT2AHDAC8 | |
| SCHEMBL4477802 | 0.84 | F10 (0.42) | USP30PTPN1CCNA2CDK2CCNA1 | |
| SCHEMBL30697767 | 0.84 | FPR2 (0.47) | PTPN1MEN1KMT2AFPR1FPR2 | |
| SCHEMBL15374430 | 0.83 | USP30 (0.51) | USP30PTPN1MEN1KMT2AHDAC8 | |
| SCHEMBL14943747 | 0.83 | USP30 (0.51) | USP30PTPN1MEN1KMT2AHDAC8 | |
| SCHEMBL29009170 | 0.80 | ALDH1A1 (0.53) | MEN1KMT2AROCK2FPR2CCNA2 | |
| SCHEMBL11312660 | 0.80 | USP30 (0.51) | USP30PTPN1MEN1KMT2AHDAC8 | |
| SCHEMBL17321486 | 0.80 | USP30 (0.48) | USP30PTPN1MEN1KMT2AHDAC8 | |
| SCHEMBL12401311 | 0.80 | USP30 (0.48) | USP30PTPN1MEN1KMT2AHDAC8 | |
| SCHEMBL5585361 | 0.80 | USP30 (0.57) | USP30PTPN1MEN1KMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245675-B | Cyclic amides as MetAP-2 inhibitors | 默克专利股份公司 | 2017-10-13 | — | — | CN | claimed |
| US-7355053-B2 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-08 | — | — | US | claimed |
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE, INC. | 2007-01-04 | — | — | US | claimed |
| US-20060019831-A1 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | US | claimed |
| EP-1556346-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-27 | — | — | EP | claimed |
| WO-2004037787-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-06 | — | — | WO | claimed |
| CN-113620873-B | Preparation method and application of zinc-containing binding group and quinoline skeleton compound | 沈阳药科大学 | 2023-12-08 | — | — | CN | disclosed |
| EP-3663282-B1 | PYRROLIDINONE HERBICIDES | FMC CORP (US) | 2022-05-18 | — | — | EP | disclosed |
| EP-3077374-B1 | PYRROLIDINONES AS HERBICIDES | FMC CORP (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2013044361-A1 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | METHYLGENE INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
| US-7355053-B2 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-08 | — | — | US | disclosed |
| US-7355053-B2 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-08 | — | — | US | disclosed |
| US-7355053-B2 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-08 | — | — | US | disclosed |
| US-20060019831-A1 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | US | disclosed |
| US-20060019831-A1 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | US | disclosed |
| US-20060019831-A1 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | US | disclosed |
| EP-1556346-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-27 | — | — | EP | disclosed |
| EP-1556346-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037787-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-06 | — | — | WO | disclosed |
| WO-2004037787-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | HGF, MET, FLT1 | USP30 3430/4885PTPN1 911/4885MEN1 3655/4885 |
| US-20060019831-A1 | 1-phenylpyrrolidine-2-one-3-carboxamides | RXFP1, REN, NPY1R | USP30 4247/4885PTPN1 371/4885MEN1 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.