Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27547370 | 0.78 | HSD17B1 (0.34) | LMNAKDM4EALDH1A1 | |
| SCHEMBL27640843 | 0.78 | SMN1; SMN2 (0.34) | KMT2AL3MBTL1HPGDCXCR2ADRA1D | |
| SCHEMBL743868 | 0.78 | LMNA (0.41) | LMNABRD4KMT2AL3MBTL1HDAC4 | |
| SCHEMBL27914881 | 0.78 | LOXL2 (0.42) | LMNAKMT2ACA2HPGDTSHR | |
| SCHEMBL8254177 | 0.77 | L3MBTL1 (0.53) | LMNABRD4KMT2AL3MBTL1HDAC1 | |
| SCHEMBL27547427 | 0.76 | HMGB1 (0.36) | KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL27678713 | 0.76 | GAA (0.41) | KMT2ACA2CA4HTTCA1 | |
| SCHEMBL28056920 | 0.76 | SMYD3 (0.40) | LMNAHPGDHTTKDM4EALDH1A1 | |
| SCHEMBL6625604 | 0.74 | LMNA (0.38) | LMNABRD4KMT2AL3MBTL1HDAC4 | |
| SCHEMBL29066672 | 0.74 | LMNA (0.44) | LMNABRD4KMT2AL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103370318-B | The Imidazopyridazine replaced | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-20 | — | — | CN | disclosed |