Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061680 | 0.87 | LTB4R (0.38) | MAOB | |
| SCHEMBL28061650 | 0.78 | TMEM97 (0.35) | MEN1KMT2A | |
| SCHEMBL28067355 | 0.77 | MMP9 (0.44) | TEAD1CYP3A4CYP2C9CYP2C19HDAC6 | |
| SCHEMBL28124735 | 0.76 | HCRTR2 (0.38) | LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28125140 | 0.74 | GLA (0.43) | LMNAMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL28093453 | 0.72 | CYP2A6 (0.39) | — | |
| SCHEMBL27809084 | 0.71 | EGFR (0.39) | MAOBKMT2A | |
| SCHEMBL28061646 | 0.70 | KDM4E (0.38) | LMNACYP3A4 | |
| SCHEMBL28294382 | 0.68 | TBXA2R (0.32) | — | |
| SCHEMBL16632922 | 0.66 | GLA (0.49) | ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636952-A | Secondary alcohol quinolinyl modulators of roryt | JANSSEN PHARMACEUTICA NV | 2016-06-01 | — | — | CN | disclosed |