2-Phenylphenol

2-Phenylphenol

SCHEMBL28061859

Cc1cccc(-c2ccccc2)c1O.Oc1ccccc1-c1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
HPGD P15428 2/20 0.65
HSD17B10 Q99714 2/20 0.65
BCL2L1 Q07817 1/20 0.65
TRPA1 O75762 2/20 0.54
HNF4A P41235 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
BACE1 P56817 1/20 0.45
ELANE P08246 2/20 0.45
CTSG P08311 1/20 0.45
ESR2 Q92731 1/20 0.44
ALOX5 P09917 1/20 0.44
ATM Q13315 1/20 0.43
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
MYC P01106 1/20 0.42
MGAM O43451 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30218224 0.92 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10BCL2L1TRPA1
SCHEMBL581901 0.92 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10BCL2L1TRPA1
Phenol SCHEMBL28344112 0.86 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10BCL2L1TRPA1
Bicarbonate SCHEMBL7942017 0.86 HNF4A (0.58) ALDH1A1HPGDHSD17B10BCL2L1TRPA1
SCHEMBL21409957 0.86 HSD17B1 (0.50) ALDH1A1HPGDHSD17B10BCL2L1TRPA1
2-Phenylphenol SCHEMBL10722979 0.86 HPGD (0.74) ALDH1A1HPGDHSD17B10BCL2L1TRPA1
2-Phenylphenol SCHEMBL29058650 0.86 HPGD (0.81) ALDH1A1HPGDHSD17B10BCL2L1HNF4A
SCHEMBL11678352 0.84 TRPA1 (0.62) ALDH1A1HPGDHSD17B10BCL2L1TRPA1
2-Phenylphenol SCHEMBL6281143 0.84 HPGD (0.77) ALDH1A1HPGDHSD17B10BCL2L1HNF4A
SCHEMBL9807339 0.81 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10BCL2L1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103154086-B Polyphenylene oxide powder and polyphenyl ether resin composition ASAHI KASEI CHEMICALS CORP. (JP) 2016-05-04 CN disclosed