Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941922 | 0.86 | TDP1 (0.58) | TDP1KMT2AL3MBTL1ATMKDM4E | |
| SCHEMBL644115 | 0.86 | TDP1 (0.58) | TDP1KMT2AL3MBTL1ATMKDM4E | |
| SCHEMBL28283295 | 0.83 | AKR1C3 (0.64) | TDP1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL11527185 | 0.83 | SMN1; SMN2 (0.71) | TDP1KMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL2639771 | 0.83 | L3MBTL1 (0.74) | TDP1KMT2AL3MBTL1ATMALDH1A1 | |
| SCHEMBL2996036 | 0.83 | ATM (0.53) | TDP1KMT2AL3MBTL1ATMKDM4E | |
| SCHEMBL9468274 | 0.82 | TDP1 (0.55) | TDP1KMT2AL3MBTL1ATMKDM4E | |
| SCHEMBL9175449 | 0.82 | TDP1 (0.54) | TDP1KMT2AALDH1A1KDM4EAKR1C3 | |
| SCHEMBL28994753 | 0.81 | TDP1 (0.62) | TDP1KMT2AALDH1A1MAPTAKR1C3 | |
| SCHEMBL3079343 | 0.81 | TDP1 (0.54) | TDP1KMT2AL3MBTL1ATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431510-A | Organic compounds | GIVAUDAN SA | 2016-03-23 | — | — | CN | disclosed |