SCHEMBL3079343

SCHEMBL3079343

CCCC(=O)Oc1ccccc1C

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.54
ATM Q13315 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
LMNA P02545 1/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
RECQL P46063 1/20 0.53
KMT2A Q03164 1/20 0.53
ALOX15 P16050 1/20 0.47
PPARG P37231 1/20 0.43
BCHE P06276 1/20 0.43
BCL9 O00512 1/20 0.42
CTNNB1 P35222 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29941922 0.90 TDP1 (0.58) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL644115 0.90 TDP1 (0.58) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL499472 0.89 KMT2A (0.67) TDP1ATML3MBTL1LMNAKDM4E
SCHEMBL9312497 0.88 KMT2A (0.59) L3MBTL1LMNAKDM4EMEN1RECQL
SCHEMBL8934268 0.88 KDM4E (0.60) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL9468274 0.87 TDP1 (0.55) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL28398105 0.86 TDP1 (0.46) TDP1ATML3MBTL1LMNAKDM4E
SCHEMBL9181885 0.86 KDM4E (0.59) TDP1ATML3MBTL1LMNAKDM4E
SCHEMBL28371332 0.86 KDM4E (0.59) TDP1ATML3MBTL1LMNAKDM4E
SCHEMBL11591925 0.86 KDM4E (0.59) TDP1ATML3MBTL1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434437-A2 Photohardenable or thermohardenable compositions and photosensitive materials utilising such photohardenable compositions THE MEAD CORPORATION (US) 1991-06-26 EP claimed
EP-3357943-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD OF PREPARING THE SAME LG CHEMICAL LTD (KR) 2022-07-20 EP disclosed
CN-113308705-A Electrooxidation preparation method of kresoxim-methyl and trifloxystrobin intermediate 湖南大学 2021-08-27 CN disclosed
CN-111620781-B Alpha-alkyl phenylacetic acid compound with high optical activity and preparation method and application thereof 南京工业大学 2021-05-25 CN disclosed
US-10906995-B2 Modifier and modified and conjugated diene-based polymer prepared using the same LG CHEM, LTD. 2021-02-02 US disclosed
CN-111620781-A Alpha-alkyl phenylacetic acid compound with high optical activity and preparation method and application thereof 南京工业大学 2020-09-04 CN disclosed
US-10450387-B2 Modifier, modified and conjugated diene-based polymer and methods for preparing them LG CHEM, LTD. (KR) 2019-10-22 US disclosed
EP-3312199-B1 AZASILANE-BASED MODIFIER, AND METHOD FOR PREPARING MODIFIED AND CONJUGATED DIENE-BASED POLYMER USING THE SAME LG CHEMICAL LTD (KR) 2019-07-03 EP disclosed
US-20190002598-A1 AZASILANE-BASED MODIFIER, AND METHOD FOR PREPARING MODIFIED AND CONJUGATED DIENE-BASED POLYMER USING THE SAME LG CHEM, LTD. (KR) 2019-01-03 US disclosed
US-20180371113-A1 MODIFIER, MODIFIED AND CONJUGATED DIENE-BASED POLYMER AND METHODS FOR PREPARING THEM LG CHEM, LTD. (KR) 2018-12-27 US disclosed
EP-1841869-A4 USE OF ATBG1 GENE FOR THE GENERATION OF TRANSGENIC PLANTS WITH INCREASED RESISTANCE TO VARIOUS ABIOTIC STRESS POSTECH FOUNDATION (KR) 2009-01-28 EP disclosed
EP-1841869-A1 USE OF ATBG1 GENE FOR THE GENERATION OF TRANSGENIC PLANTS WITH INCREASED RESISTANCE TO VARIOUS ABIOTIC STRESS Postech Foundation (KR) 2007-10-10 EP disclosed
WO-2006068442-A1 USE OF ATBG1 GENE FOR THE GENERATION OF TRANSGENIC PLANTS WITH INCREASED RESISTANCE TO VARIOUS ABIOTIC STRESS POSTECH FOUNDATION (KR) 2006-06-29 WO disclosed
US-6600080-B1 Method of alcohols such as cyclohexanedimethanol, a benzyl ester is obtained, for example, by the reaction between a benzyl compound and carboxylic acid in the presence of oxygen and a catalyst including palladium, gold ultra fine particles NIPPON SHOKUBAI CO., LTD. (JP) 2003-07-29 US disclosed
EP-1090902-A2 Method for producing alcohols such as cyclohexanedimethanol Nippon Shokubai Co., Ltd. (JP) 2001-04-11 EP disclosed
US-5658924-A CIRCULATORY, RESPIRATORY, NERVOUS SYSTEM DISORDERS THE GREEN CROSS CORPORATION (JP) 1997-08-19 US disclosed
EP-0728128-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1996-08-28 EP disclosed
EP-0670320-A1 1,8-NAPHTHYRIDIN-2-ONE DERIVATIVE AND USE THEREOF- THE GREEN CROSS CORPORATION (JP) 1995-09-06 EP disclosed
WO-1995013262-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1995-05-18 WO disclosed
EP-0434437-A2 Photohardenable or thermohardenable compositions and photosensitive materials utilising such photohardenable compositions THE MEAD CORPORATION (US) 1991-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190002598-A1 AZASILANE-BASED MODIFIER, AND METHOD FOR PREPARING MODIFIED AND CONJUGATED DIENE-BASED POLYMER USING THE SAME RIF1, RAE1, TRRAP TDP1 1209/4885ATM 2956/4885L3MBTL1 4730/4885
US-10450387-B2 Modifier, modified and conjugated diene-based polymer and methods for preparing them UFM1, F13A1, ITGAM TDP1 2436/4885ATM 3156/4885L3MBTL1 3716/4885
US-10906995-B2 Modifier and modified and conjugated diene-based polymer prepared using the same RIF1, FDFT1, CAD TDP1 1937/4885ATM 3097/4885L3MBTL1 4294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.