SCHEMBL28062170

SCHEMBL28062170

CC1CCC(C(C)C)C(OC(=O)C(N)=O)C1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.58
HPGD P15428 2/20 0.58
EPHX1 P07099 3/20 0.56
CYP19A1 P11511 2/20 0.50
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.47
LMNA P02545 2/20 0.45
TRPA1 O75762 2/20 0.44
TRPM8 Q7Z2W7 2/20 0.44
TSHR P16473 2/20 0.44
USP2 O75604 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13468949 1.00 ALDH1A1 (0.58) ALDH1A1HPGDEPHX1CYP19A1MAPT
SCHEMBL14405186 1.00 ALDH1A1 (0.58) ALDH1A1HPGDEPHX1CYP19A1MAPT
SCHEMBL16194851 0.90 EPHX1 (0.61) ALDH1A1HPGDEPHX1CYP19A1MAPT
SCHEMBL6387314 0.90 EPHX1 (0.61) ALDH1A1HPGDEPHX1CYP19A1MAPT
SCHEMBL27914203 0.87 EPHX1 (0.58) ALDH1A1HPGDEPHX1CYP19A1MAPT
SCHEMBL5495940 0.87 EPHX1 (0.58) ALDH1A1HPGDEPHX1CYP19A1MAPT
SCHEMBL10199136 0.87 EPHX1 (0.58) ALDH1A1HPGDEPHX1CYP19A1MAPT
SCHEMBL2125537 0.87 EPHX1 (0.58) ALDH1A1HPGDEPHX1CYP19A1MAPT
SCHEMBL584831 0.87 EPHX1 (0.58) ALDH1A1HPGDEPHX1CYP19A1MAPT
Acetamide SCHEMBL28726347 0.86 EPHX1 (0.52) ALDH1A1HPGDEPHX1CYP19A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026525-A1 HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS SYMRISE AG (DE) 2025-02-06 WO claimed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 EP claimed
CN-118984825-A Novel cooling agent and preparation containing same 西姆莱斯股份公司 2024-11-19 CN claimed
EP-4452941-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-10-30 EP claimed
CN-117813077-A Composition and method for producing the same 西姆莱斯股份公司 2024-04-02 CN claimed
CN-117615798-A Composition for combating malodour 西姆莱斯股份公司 2024-02-27 CN claimed
WO-2023144326-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO claimed
WO-2023143741-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO claimed
WO-2022105986-A1 NOVEL COOLING AGENTS AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2022-05-27 WO claimed
EP-3996505-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS Bedoukian Research, Inc. (US) 2022-05-18 EP claimed
EP-3996506-A1 FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS Bedoukian Research, Inc. (US) 2022-05-18 EP claimed
US-20260101914-A1 VANILLA COMPOSITION FIRMENICH & CIE (CH) 2026-04-16 US disclosed
US-20250344733-A1 FLAVOR NANOEMULSIONS FOR BEVERAGE AND PERSONAL CARE APPLICATIONS FIRMENICH SA (CH) 2025-11-13 US disclosed
EP-4503939-A1 FLAVOR NANOEMULSIONS FOR BEVERAGE AND PERSONAL CARE APPLICATIONS Firmenich SA (CH) 2025-02-12 EP disclosed
WO-2025026525-A1 HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS SYMRISE AG (DE) 2025-02-06 WO disclosed
WO-2022105986-A1 NOVEL COOLING AGENTS AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2022-05-27 WO disclosed
WO-2022101424-A1 CITRUS OIL EXTRACT FIRMENICH SA (CH) 2022-05-19 WO disclosed
EP-3996506-A1 FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS Bedoukian Research, Inc. (US) 2022-05-18 EP disclosed
EP-3996505-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS Bedoukian Research, Inc. (US) 2022-05-18 EP disclosed
CN-105473002-A 1H-PYRROLE-2,4-DICARBONYL-DERIVATIVES AND THEIR USE AS FLAVORING AGENTS FRESENIUS KABI DE GMBH 2016-04-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260101914-A1 VANILLA COMPOSITION TAS2R19, TAS2R9, TAS2R39 ALDH1A1 534/4885HPGD 217/4885EPHX1 482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.