Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914203 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL584831 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL10199136 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL2125537 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL3380308 | 0.90 | EPHX1 (0.53) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL24026949 | 0.90 | EPHX1 (0.49) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL18629605 | 0.90 | EPHX1 (0.49) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| Nornitrogen Mustard SCHEMBL3380310 | 0.87 | EPHX1 (0.51) | EPHX1ALDH1A1HPGDCYP19A1TRPM8 | |
| SCHEMBL13468949 | 0.87 | ALDH1A1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL28062170 | 0.87 | ALDH1A1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254298-A1 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS | APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUP (US) | 2007-11-01 | — | — | US | disclosed |
| US-20060188915-A1 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHODS OF DNA SEQUENCING AND FRAGMENT ANALYSIS | APPLERA CORPORATION (US) | 2006-08-24 | — | — | US | disclosed |
| US-7038063-B2 | Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis | APPLERA CORPORATION (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040229235-A1 | Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis | APPLERA CORPORATION | 2004-11-18 | — | — | US | disclosed |
| US-6649769-B2 | For labelling a polynucleotides | APPLERA CORPORATION | 2003-11-18 | — | — | US | disclosed |
| US-20030055243-A1 | Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis | PE CORPORATION (NY) | 2003-03-20 | — | — | US | disclosed |
| US-6448407-B1 | LABELS FOR SUCH AS NUCLEOTIDES, NUCLEOSIDES, POLYPEPTIDES, POLYNUCLEOTIDES AND CARBOHYDRATES; SEQUENCING, FRAGMENT ANALYSIS, OLIGONUCLEOTIDE LIGATION, AMPLIFICATION, MINISEQUENCING, AND PRIMER EXTENSION | PE CORPORATION (NY) | 2002-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060188915-A1 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHODS OF DNA SEQUENCING AND FRAGMENT ANALYSIS | CHRNB3, CHRNB4, SPR | EPHX1 4388/4885ALDH1A1 3581/4885HPGD 458/4885 |
| US-20070254298-A1 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS | CHRNB3, CHRNB4, SPR | EPHX1 4436/4885ALDH1A1 3563/4885HPGD 479/4885 |
| US-20040229235-A1 | Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis | CHRNB3, CHRNB4, SPR | EPHX1 4388/4885ALDH1A1 3581/4885HPGD 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.