Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914203 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL5495940 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL10199136 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL2125537 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL3380308 | 0.90 | EPHX1 (0.53) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL24026949 | 0.90 | EPHX1 (0.49) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL18629605 | 0.90 | EPHX1 (0.49) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| Nornitrogen Mustard SCHEMBL3380310 | 0.87 | EPHX1 (0.51) | EPHX1ALDH1A1HPGDCYP19A1TRPM8 | |
| SCHEMBL13468949 | 0.87 | ALDH1A1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL28062170 | 0.87 | ALDH1A1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103002868-B | As the carbamic acid cyclohexyl compound of active fat melting composition | SYMRISE AG (DE) | 2016-05-04 | — | — | CN | claimed |
| CN-103025310-B | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2016-01-27 | — | — | CN | claimed |
| CN-101679278-B | Process for the preparation of dibenzo [B,D]azepin-6-one derivative | HOFFMANN LA ROCHE | 2013-08-14 | — | — | CN | claimed |
| EP-2164830-B1 | PROCESS FOR THE PREPARATION OF DIBENZO [B,D]AZEPIN-6-ONE DERIVATIVE | HOFFMANN LA ROCHE (CH) | 2013-05-29 | — | — | EP | claimed |
| CN-103025310-A | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE GMBH & CO KG | 2013-04-03 | — | — | CN | claimed |
| CN-103002868-A | Cyclohexyl carbamate compounds as active anti-cellulite ingredients | SYMRISE GMBH & CO KG | 2013-03-27 | — | — | CN | claimed |
| EP-2164830-A2 | PROCESS FOR THE PREPARATION OF DIBENZO [B,D]AZEPIN-6-ONE DERIVATIVE | F. Hoffmann-Roche AG (CH) | 2010-03-24 | — | — | EP | claimed |
| CN-101679278-A | Process for the preparation of dibenzo [B, D] aza-6-one derivatives | HOFFMANN LA ROCHE | 2010-03-24 | — | — | CN | claimed |
| US-7579464-B2 | Process for preparation of enantiomerically pure compounds | HOFFMANN-LA ROCHE INC. (US) | 2009-08-25 | — | — | US | claimed |
| WO-2008145525-A2 | PROCESS FOR THE PREPARATION OF DIBENZO [B,D]AZEPIN-6-ONE DERIVATIVE | F. HOFFMANN-LA ROCHE AG (CH) | 2008-12-04 | — | — | WO | claimed |
| US-20080293933-A1 | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE COMPOUNDS | HOFFMANN-LA ROCHE, INC. | 2008-11-27 | — | — | US | claimed |
| US-20220117881-A1 | A HAIR CARE COMPOSITION | SYMRISE AG (DE) | 2022-04-21 | — | — | US | disclosed |
| CN-113730292-A | Whitening essence and preparation method and application thereof | 深圳市靓丽人生化妆品有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113226267-A | Hair care composition | 西姆莱斯股份公司 | 2021-08-06 | — | — | CN | disclosed |
| EP-3849505-A1 | A HAIR CARE COMPOSITION | Symrise AG (DE) | 2021-07-21 | — | — | EP | disclosed |
| US-5229381-A | Inhibitors of leukocyte enzyme elastase | MERCK & CO., INC. (US) | 1993-07-20 | — | — | US | disclosed |
| US-5180736-A | Treatment and prevention of brain disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0481671-A1 | New substituted azetidinones as anti-inflammatory and antidegenerative agents | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |
| US-5071853-A | Amine-substituted hexahydroindeno(2,1-b)pyrroles, -indeno(2,1-c)pyridines or -indeno(2,1-d)azepines; cerebral ischemia or infarction | WARNER-LAMBERT COMPANY | 1991-12-10 | — | — | US | disclosed |
| EP-0388977-A2 | Polycyclic amines useful as cerebrovascular agents | WARNER-LAMBERT COMPANY (US) | 1990-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293933-A1 | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE COMPOUNDS | BACE1, BACE2, BCHE | EPHX1 504/4885ALDH1A1 923/4885HPGD 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.