Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26096557 | 0.86 | ABL1 (0.54) | CYP2D6TSHRACHEOPRM1SIGMAR1 | |
| SCHEMBL19148467 | 0.84 | HTR2A (0.67) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18536613 | 0.81 | ACHE (0.68) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL26097974 | 0.80 | OPRM1 (0.46) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| SCHEMBL26097422 | 0.79 | OPRM1 (0.52) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5367392 | 0.79 | HTR2A (0.71) | HTR2AACHEOPRM1SIGMAR1 | |
| SCHEMBL27376720 | 0.78 | OPRM1 (0.58) | HTR2AOPRM1SIGMAR1 | |
| SCHEMBL27360998 | 0.78 | HTR2A (0.52) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| Propionamide SCHEMBL29025290 | 0.77 | SIGMAR1 (0.62) | HTR2ACYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL8006204 | 0.76 | CCR3 (0.63) | HTR2AACHESIGMAR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105407925-A | Manufacturing process for effervescent dosage forms | MYLAN INC | 2016-03-16 | — | — | CN | disclosed |