SCHEMBL28062771

SCHEMBL28062771

C=C1CCCC(OC(N)=O)C1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.34
PARP10 Q53GL7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28370759 0.80
SCHEMBL9957309 0.79 THRB (0.41) ATMPARP10
SCHEMBL29090337 0.79 THRB (0.41) ATMPARP10
SCHEMBL22105320 0.77 CYP19A1 (0.31)
SCHEMBL22105022 0.76 HPGD (0.32)
SCHEMBL29090338 0.75 ATM (0.33) ATMPARP10
SCHEMBL28407513 0.74 THRB (0.37) ATMPARP10
SCHEMBL28348956 0.74 DPP4 (0.36)
SCHEMBL10067466 0.73 ATM (0.45) ATMPARP10
SCHEMBL113287 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105849099-A Polycyclic inhibitors of cyclin-dependent kinase 7 (CDK7) 达纳-法伯癌症研究所股份有限公司 2016-08-10 CN disclosed