Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5241382 | 0.76 | EGFR (0.48) | EGFRSRCSMN1; SMN2ALDH1A1 | |
| SCHEMBL7490158 | 0.75 | EGFR (0.58) | MAPTEGFRSRCMEN1KMT2A | |
| SCHEMBL7708920 | 0.74 | MAPT (0.67) | MAPTMEN1KMT2ALMNAF2R | |
| SCHEMBL2846714 | 0.69 | CDK2 (0.56) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28207452 | 0.68 | KIF11 (0.50) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL2851292 | 0.68 | L3MBTL1 (0.51) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3694723 | 0.68 | L3MBTL1 (0.51) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2852352 | 0.68 | HTT (0.58) | MAPTMEN1KMT2ANPSR1CDK2 | |
| SCHEMBL22463722 | 0.68 | EGFR (0.54) | MAPTEGFRSRCMEN1KMT2A | |
| SCHEMBL18928573 | 0.67 | MAPT (0.82) | MAPTMEN1KMT2ALMNAF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646327-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |