Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28001830 | 1.00 | UGT2B7 (0.50) | UGT2B7TRPA1PTGS1CACNA1CLMNA | |
| SCHEMBL29403039 | 0.82 | TRPA1 (0.43) | TRPA1PTGS1CACNA1CLMNATP53 | |
| SCHEMBL14182599 | 0.82 | TRPA1 (0.43) | TRPA1PTGS1CACNA1CLMNATP53 | |
| SCHEMBL822085 | 0.82 | TRPA1 (0.43) | TRPA1PTGS1CACNA1CLMNATP53 | |
| SCHEMBL172412 | 0.81 | TDP1 (0.50) | UGT2B7TRPA1PTGS1CACNA1CLMNA | |
| SCHEMBL1926385 | 0.79 | AKR1C3 (0.49) | UGT2B7TRPA1PTGS1CACNA1CLMNA | |
| SCHEMBL13711036 | 0.79 | UGT2B7 (0.45) | UGT2B7TRPA1PTGS1CACNA1CLMNA | |
| SCHEMBL13254985 | 0.79 | TDP1 (0.48) | UGT2B7TRPA1PTGS1CACNA1CLMNA | |
| SCHEMBL14966985 | 0.79 | UGT2B7 (0.45) | UGT2B7TRPA1PTGS1CACNA1CLMNA | |
| SCHEMBL20488728 | 0.79 | AKR1C3 (0.49) | UGT2B7TRPA1PTGS1CACNA1CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111141849-B | Liquid phase detection separation method for positional isomer of dexmedetomidine initial raw material | 江苏开元药业有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-113325096-B | Detection method of 1- (2,3-dimethylphenyl) ethanol related substances | 石家庄四药有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-113325096-A | Detection method of 1- (2, 3-dimethylphenyl) ethanol related substances | 石家庄四药有限公司 | 2021-08-31 | — | — | CN | claimed |
| CN-111141849-A | Liquid phase detection and separation method for positional isomer of dexmedetomidine starting material | 江苏开元药业有限公司 | 2020-05-12 | — | — | CN | claimed |
| CN-111141849-B | Liquid phase detection separation method for positional isomer of dexmedetomidine initial raw material | 江苏开元药业有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-113325096-B | Detection method of 1- (2,3-dimethylphenyl) ethanol related substances | 石家庄四药有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-113325096-A | Detection method of 1- (2, 3-dimethylphenyl) ethanol related substances | 石家庄四药有限公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-111141849-A | Liquid phase detection and separation method for positional isomer of dexmedetomidine starting material | 江苏开元药业有限公司 | 2020-05-12 | — | — | CN | disclosed |
| EP-2651899-B1 | SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2017-05-31 | — | — | EP | disclosed |
| CN-104311392-A | Synthesis of R-1-(3, 4-dimethylphenyl) ethanol and ester thereof | WANG TONGJUN | 2015-01-28 | — | — | CN | disclosed |
| US-8623889-B2 | Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof | GENENTECH, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8133869-B2 | And oxidized natural lignin phenols with a low molecular weigh; disinfecting, microbicidal, root growth enhancing activity | Lopretti, Mary (UY) | 2012-03-13 | — | — | US | disclosed |
| US-20080242663-A1 | NOVEL PYRIMIDINE DERIVATIVES 698 | ASTRAZENECA AB (SE) | 2008-10-02 | — | — | US | disclosed |
| US-20080220974-A1 | COMPOSITIONS CONTAINING POLY[BETA(1,4)-2-AMINO-2-DEOXYGLUCOPYRANOSE] OLIGOMERS IN A SOLUTION OF MODIFIED LIGNIN PHENOLS AND THEIR USES | LOPRETTI MARY | 2008-09-11 | — | — | US | disclosed |
| EP-0523697-B1 | Color-developing compositions and their use | MITSUI TOATSU CHEMICALS (JP) | 1997-04-02 | — | — | EP | disclosed |
| US-5447901-A | Color-developing sheet: base material coated with composition of /a/ multivalent metal-modified salicylic acid resin formed from salicylic acid, a benzyl compound and optional styrene and /b/ analogous resin free of salicylic acid | MITSUI TOATSU CHEMICAL, INC. (JP) | 1995-09-05 | — | — | US | disclosed |
| US-5376615-A | Pressure sensitive elements containing a salicylic acid resin and a phenolic resin | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0523697-A1 | Color-developing compositions and their use | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-5023366-A | Reacted with a benzyl halide, alcohol or ether; for pressure sensitive elements | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-06-11 | — | — | US | disclosed |
| EP-0268878-A2 | Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242663-A1 | NOVEL PYRIMIDINE DERIVATIVES 698 | EPHB4, EPHB1, NME2 | UGT2B7 755/4885TRPA1 4263/4885PTGS1 1695/4885 |
| US-20080220974-A1 | COMPOSITIONS CONTAINING POLY[BETA(1,4)-2-AMINO-2-DEOXYGLUCOPYRANOSE] OLIGOMERS IN A SOLUTION OF MODIFIED LIGNIN PHENOLS AND THEIR USES | PGLS, PLOD1, DAO | UGT2B7 463/4885TRPA1 1380/4885PTGS1 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.