SCHEMBL28063263

SCHEMBL28063263

CCCCC(=O)O[SiH2]CCC

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.42
CES2 O00748 2/20 0.42
DGKA P23743 1/20 0.42
LMNA P02545 2/20 0.39
ALDH1A1 P00352 3/20 0.39
TP53 P04637 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
PAM P19021 2/20 0.38
CA1 P00915 1/20 0.38
MAPT P10636 2/20 0.37
MAPK1 P28482 1/20 0.37
MIF P14174 1/20 0.37
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6658190 0.87 DGKA (0.42) CES1CES2DGKALMNAALDH1A1
SCHEMBL28063132 0.86 ALDH1A1 (0.50) CES1CES2DGKALMNAALDH1A1
SCHEMBL28063124 0.86 NAAA (0.45) DGKALMNAALDH1A1KMT2A
SCHEMBL6662620 0.83 DGKA (0.48) CES1CES2DGKALMNAALDH1A1
SCHEMBL6663763 0.83 DGKA (0.48) CES1CES2DGKALMNAALDH1A1
SCHEMBL28063226 0.82 LMNA (0.42) DGKALMNAALDH1A1KDM4EMEN1
SCHEMBL6659112 0.81 DGKA (0.45) CES1CES2DGKALMNAALDH1A1
SCHEMBL6658192 0.80 TSHR (0.48) ALDH1A1MEN1KMT2APAMMAPT
SCHEMBL6555637 0.80 DGKA (0.37) CES1CES2DGKALMNAALDH1A1
SCHEMBL28063140 0.79 LMNA (0.40) DGKALMNAMAPTMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103391947-B Stabilization of polymers containing hydrolyzable functional groups 株式会社普利司通 2016-08-24 CN disclosed