Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064079 | 0.88 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28064102 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL28088219 | 0.83 | PPARG (0.36) | SMN1; SMN2PPARDPPARAPPARG | |
| SCHEMBL28064075 | 0.83 | KDM4E (0.39) | KDM4EHPGDRAB9ANPC1GLA | |
| SCHEMBL28064167 | 0.83 | KCNA5 (0.46) | KDM4EHPGDRAB9ANPC1GLA | |
| SCHEMBL28088153 | 0.82 | HRH3 (0.37) | KDM4EHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL2229121 | 0.82 | GRIN2B (0.42) | KDM4EHPGDRAB9ANPC1GLA | |
| SCHEMBL28064203 | 0.82 | PPARG (0.46) | PPARDPPARAPPARG | |
| SCHEMBL28064084 | 0.81 | TEAD1 (0.47) | ALDH1A1PPARDPPARALMNAPPARG | |
| SCHEMBL28088222 | 0.81 | PPARG (0.37) | RAB9ANPC1KMT2AMEN1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |