Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.46 |
| ▸ | PPARD | Q03181 | 9/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28088194 | 0.91 | PPARG (0.40) | PPARGPPARDPPARAGRM5F10 | |
| SCHEMBL28088222 | 0.88 | PPARG (0.37) | PPARGPPARDPPARAGRM5F10 | |
| SCHEMBL28064060 | 0.87 | LTA4H (0.39) | PPARGPPARDPPARAGRM5 | |
| SCHEMBL28064163 | 0.85 | ALDH1A1 (0.38) | PPARGPPARDPPARAHTR7 | |
| SCHEMBL28064069 | 0.85 | PPARG (0.37) | PPARGPPARDPPARAGRM5 | |
| SCHEMBL28064076 | 0.83 | PPARG (0.47) | PPARGPPARDPPARAGRM5CYP1A2 | |
| SCHEMBL2229387 | 0.82 | GRM5 (0.46) | PPARGPPARDPPARAGRM5CYP1A2 | |
| SCHEMBL28064067 | 0.82 | KDM4E (0.40) | PPARGPPARDPPARA | |
| SCHEMBL28064102 | 0.81 | KDM4E (0.41) | HTR7 | |
| SCHEMBL28064084 | 0.81 | TEAD1 (0.47) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |