Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064086 | 0.85 | LTA4H (0.39) | MAPTSMN1; SMN2KMT2AHCRTR1HCRTR2 | |
| SCHEMBL28088346 | 0.84 | RAB9A (0.38) | HRH3RAB9ANPC1MAPTPKM | |
| SCHEMBL2227353 | 0.82 | GRIN2B (0.41) | HRH3RAB9ANPC1PKMKDM4E | |
| SCHEMBL28088194 | 0.82 | PPARG (0.40) | MAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL28064067 | 0.82 | KDM4E (0.40) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL28064102 | 0.82 | KDM4E (0.41) | KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL28064203 | 0.80 | PPARG (0.46) | — | |
| SCHEMBL28064163 | 0.80 | ALDH1A1 (0.38) | MAPTKDM4ESMN1; SMN2HPGDKMT2A | |
| SCHEMBL28064081 | 0.80 | PTGDR2 (0.40) | KMT2AMEN1 | |
| SCHEMBL28064084 | 0.80 | TEAD1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |